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IN VITRO SENSITIVITY OF CHOLINESTERASES AND [(3)H]OXOTREMORINE-M BINDING IN HEART AND BRAIN OF ADULT AND AGING RATS TO ORGANOPHOSPHORUS ANTICHOLINESTERASES

Organophosphorus (OP) insecticides elicit toxicity via acetylcholinesterase inhibition, allowing acetylcholine accumulation and excessive stimulation of cholinergic receptors. Some OP insecticides bind to additional macromolecules including butyrylcholinesterase and cholinergic receptors. While neur...

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Bibliographische Detailangaben
Hauptverfasser: Mirajkar, Nikita, Pope, Carey N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572567/
https://ncbi.nlm.nih.gov/pubmed/18761328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.08.001
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