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Comparative Effects of Oral Chlorpyrifos Exposure on Cholinesterase Activity and Muscarinic Receptor Binding in Neonatal and Adult Rat Heart

Organophosphorus (OP) pesticides elicit acute toxicity by inhibiting acetylcholinesterase (AChE), the enzyme responsible for inactivating acetylcholine (ACh) at cholinergic synapses. A number of OP toxicants have also been reported to interact directly with muscarinic receptors, in particular the M(...

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Detalhes bibliográficos
Main Authors: Howard, Marcia D., Mirajkar, Nikita, Karanth, Subramanya, Pope, Carey N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954647/
https://ncbi.nlm.nih.gov/pubmed/17644233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2007.05.030
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