IN VITRO SENSITIVITY OF CHOLINESTERASES AND [(3)H]OXOTREMORINE-M BINDING IN HEART AND BRAIN OF ADULT AND AGING RATS TO ORGANOPHOSPHORUS ANTICHOLINESTERASES

Organophosphorus (OP) insecticides elicit toxicity via acetylcholinesterase inhibition, allowing acetylcholine accumulation and excessive stimulation of cholinergic receptors. Some OP insecticides bind to additional macromolecules including butyrylcholinesterase and cholinergic receptors. While neur...

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Bibliographic Details
Main Authors: Mirajkar, Nikita, Pope, Carey N.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572567/
https://ncbi.nlm.nih.gov/pubmed/18761328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.08.001
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