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IN VITRO SENSITIVITY OF CHOLINESTERASES AND [(3)H]OXOTREMORINE-M BINDING IN HEART AND BRAIN OF ADULT AND AGING RATS TO ORGANOPHOSPHORUS ANTICHOLINESTERASES

Organophosphorus (OP) insecticides elicit toxicity via acetylcholinesterase inhibition, allowing acetylcholine accumulation and excessive stimulation of cholinergic receptors. Some OP insecticides bind to additional macromolecules including butyrylcholinesterase and cholinergic receptors. While neur...

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Detalhes bibliográficos
Main Authors: Mirajkar, Nikita, Pope, Carey N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572567/
https://ncbi.nlm.nih.gov/pubmed/18761328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.08.001
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