Stable Isotope-Coded Quaternization for Comparative Quantification of Estrogen Metabolites by High-Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry

A fast and sensitive LC-ESI-MS method is described for the comparative quantification of 16 estrogen metabolites based on the derivatization of estrogens with a novel derivatizing reagent, N-methyl-nicotinic acid N-hydroxysuccinimide ester (C1-NA-NHS). The process introduces a quaternary amine to th...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang, Wen-Chu, Regnier, Fred E., Sliva, Dan, Adamec, Jiri
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572562/
https://ncbi.nlm.nih.gov/pubmed/18595786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.06.026
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items