DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

Histone H3K9 methylation is required for DNA methylation and silencing of repetitive elements in plants and filamentous fungi. In mammalian cells however, deletion of the H3K9 histone methyltransferases (HMTases) Suv39h1 and Suv39h2 does not affect DNA methylation of the endogenous retrovirus murine...

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Detalhes bibliográficos
Main Authors: Dong, Kevin B, Maksakova, Irina A, Mohn, Fabio, Leung, Danny, Appanah, Ruth, Lee, Sandra, Yang, Hao W, Lam, Lucia L, Mager, Dixie L, Schübeler, Dirk, Tachibana, Makoto, Shinkai, Yoichi, Lorincz, Matthew C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572176/
https://ncbi.nlm.nih.gov/pubmed/18818693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.193
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