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NMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsA

Structural studies of polytopic membrane proteins are often hampered by the vagaries of these proteins in membrane mimetic environments and by the difficulties in handling them with conventional techniques. Designing and creating water-soluble analogues with preserved native structures offer an attr...

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Detalhes bibliográficos
Main Authors: Ma, Dejian, Tillman, Tommy S., Tang, Pei, Meirovitch, Eva, Eckenhoff, Roderic, Carnini, Anna, Xu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572164/
https://ncbi.nlm.nih.gov/pubmed/18948596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805501105
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