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INACTIVATION OF AN INVERTEBRATE ACETYLCHOLINESTERASE BY SULFHYDRYL REAGENTS: A RECONSIDERATION OF THE IMPLICATIONS FOR INSECTICIDE DESIGN
Previously we used site-directed mutagenesis, in vitro expression, and molecular modeling to investigate the inactivation of an invertebrate acetylcholinesterase, cholinesterase 2 from amphioxus, by the sulfhydryl reagents 5,5’-dithiobis(2-nitrobenzoic acid) (DTNB) and N-ethylmaleimide (NEM). We cre...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571039/ https://ncbi.nlm.nih.gov/pubmed/18384763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2008.02.006 |
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