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Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions.

The role of SH groups in opiate-receptor interactions has been further examined. In activation by N-ethylmaleimide of sterospecific opiate binding by rat brain membrane fractions follows pseudo-first order kinetics and exhibits strong temperature dependence. The kinetics indicate that alkylation of...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Simon, E J, Groth, J
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1975
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1056036/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.6.2404
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