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Evolution of the ssrA degradation tag in Mycoplasma: Specificity switch to a different protease

Stalled ribosomes in bacteria are rescued by the tmRNA system. In this process, the nascent polypeptide is modified by the addition of a short C-terminal sequence called the ssrA tag, which is encoded by tmRNA and allows normal termination and release of ribosomal subunits. In most bacteria, ssrA-ta...

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Autori principali: Gur, Eyal, Sauer, Robert T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570983/
https://ncbi.nlm.nih.gov/pubmed/18852454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808802105
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