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The AAA+ FtsH protease degrades an ssrA-tagged model protein in the inner membrane of E. coli
In eubacteria, the tmRNA system frees ribosomes that stall during protein synthesis and adds an ssrA tag to the incompletely translated polypeptide to target it for degradation. The AAA+ ClpXP protease degrades most ssrA-tagged proteins in the E. coli cytoplasm and was recently shown to degrade an s...
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| Veröffentlicht in: | Biochemistry |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5218843/ https://ncbi.nlm.nih.gov/pubmed/27677373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00920 |
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