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Colchicine prevents tumor necrosis factor-induced toxicity in vivo.
Tumor necrosis factor (TNF) toxicity was induced in vivo by intravenous administration of 15 micrograms of recombinant murine TNF-alpha per kg to galactosamine-sensitized mice. Within 8 h, the animals developed a fulminant hepatitis. Intravenous administration of 0.5 mg of colchicine per kg at 19 an...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563785/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1941-1945.1992 |
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