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Colchicine prevents tumor necrosis factor-induced toxicity in vivo.

Tumor necrosis factor (TNF) toxicity was induced in vivo by intravenous administration of 15 micrograms of recombinant murine TNF-alpha per kg to galactosamine-sensitized mice. Within 8 h, the animals developed a fulminant hepatitis. Intravenous administration of 0.5 mg of colchicine per kg at 19 an...

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Bibliografische gegevens
Hoofdauteurs: Tiegs, G, Freudenberg, M A, Galanos, C, Wendel, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC257098/
https://ncbi.nlm.nih.gov/pubmed/1563785
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