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Protein Conjugation with Amphiphilic Block Copolymers for Enhanced Cellular Delivery

Modification of a model protein, horseradish peroxidase (HRP), with amphiphilic block copolymer poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (Pluronic), was previously shown to enhance the transport of this protein across the blood—brain barrier in vivo and brain microvessel e...

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Autores principales: Yi, Xiang, Batrakova, Elena, Banks, William A., Vinogradov, Serguei, Kabanov, Alexander V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570949/
https://ncbi.nlm.nih.gov/pubmed/18447367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700443k
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