Interaction with RPA Is Necessary for Rad52 Repair Center Formation and for Its Mediator Activity

Homologous recombination (HR) is a major DNA repair pathway and therefore essential for maintaining the integrity of the genome. HR is catalyzed by proteins encoded by genes of the RAD52 epistasis group, including the recombinase Rad51 and its mediator Rad52. HR proteins fused with green fluorescent...

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Hlavní autoři: Plate, Iben, Hallwyl, Swee C. L., Shi, Idina, Krejci, Lumir, Müller, Christian, Albertsen, Line, Sung, Patrick, Mortensen, Uffe H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570898/
https://ncbi.nlm.nih.gov/pubmed/18703507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804881200
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