γ-Secretase Activation of Notch Signaling Regulates the Balance of Proximal and Distal Fates in Progenitor Cells of the Developing Lung

Little is known about the mechanisms by which the lung epithelial progenitors are initially patterned and how proximal-distal boundaries are established and maintained when the lung primordium forms and starts to branch. Here we identified a number of Notch pathway components in respiratory progenit...

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Bibliografiske detaljer
Main Authors: Tsao, Po-Nien, Chen, Felicia, Izvolsky, Konstantin I., Walker, Janice, Kukuruzinska, Maria A., Lu, Jining, Cardoso, Wellington V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Molecular Basis of Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570893/
https://ncbi.nlm.nih.gov/pubmed/18694942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801565200
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