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γ-Secretase Activation of Notch Signaling Regulates the Balance of Proximal and Distal Fates in Progenitor Cells of the Developing Lung

Little is known about the mechanisms by which the lung epithelial progenitors are initially patterned and how proximal-distal boundaries are established and maintained when the lung primordium forms and starts to branch. Here we identified a number of Notch pathway components in respiratory progenit...

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Detalhes bibliográficos
Main Authors: Tsao, Po-Nien, Chen, Felicia, Izvolsky, Konstantin I., Walker, Janice, Kukuruzinska, Maria A., Lu, Jining, Cardoso, Wellington V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570893/
https://ncbi.nlm.nih.gov/pubmed/18694942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801565200
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