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How a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound Peptide
We determined the crystal structures of the T cell receptor (TCR)-like antibody 25-D1.16 Fab fragment bound to a complex of SIINFEKL peptide from ovalbumin and the H-2K(b) molecule. Remarkably, this antibody directly “reads” the structure of the major histocompatibility complex (MHC)-bound peptide,...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570882/ https://ncbi.nlm.nih.gov/pubmed/18703505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804996200 |
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