The Aryl Hydrocarbon Receptor Attenuates Tobacco Smoke-induced Cyclooxygenase-2 and Prostaglandin Production in Lung Fibroblasts through Regulation of the NF-κB Family Member RelB

Diseases such as chronic obstructive pulmonary disease and lung cancer caused by cigarette smoke affect millions of people worldwide. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that influences responses to certain environmental pollutants such as tobacco smoke. Ho...

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Hlavní autoři: Baglole, Carolyn J., Maggirwar, Sanjay B., Gasiewicz, Thomas A., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570856/
https://ncbi.nlm.nih.gov/pubmed/18697742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800685200
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