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Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity

Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito initiate a malaria infection in humans. Here we report the first proteomic comparison of different parasite stages from the mosquito—early and late oocysts containing midgut sporozoites, and the mature, infectious...

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Autors principals: Lasonder, Edwin, Janse, Chris J., van Gemert, Geert-Jan, Mair, Gunnar R., Vermunt, Adriaan M. W., Douradinha, Bruno G., van Noort, Vera, Huynen, Martijn A., Luty, Adrian J. F., Kroeze, Hans, Khan, Shahid M., Sauerwein, Robert W., Waters, Andrew P., Mann, Matthias, Stunnenberg, Hendrik G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570797/
https://ncbi.nlm.nih.gov/pubmed/18974882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000195
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