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Regulation of BAG-1-IRES-mediated translation following chemotoxic stress

There are three major isoforms of BAG-1 in mammalian cells, termed BAG-1L (p50), BAG-1M (p46) and BAG-1S (p36) that function as pro-survival proteins and are associated with tumourigenesis and chemo-resistance. Initiation of BAG-1 protein synthesis can occur by both cap-dependent and cap-independent...

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Detalhes bibliográficos
Main Authors: Dobbyn, Helen C., Hill, Kirsti, Hamilton, Tiffany L., Spriggs, Keith A., Pickering, Becky M., Coldwell, Mark J, de Moor, Cornelia H., Bushell, Martin, Willis, Anne E
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570717/
https://ncbi.nlm.nih.gov/pubmed/17700523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210723
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