Bag-1 Internal Ribosome Entry Segment Activity Is Promoted by Structural Changes Mediated by Poly(rC) Binding Protein 1 and Recruitment of Polypyrimidine Tract Binding Protein 1

We have shown previously that an internal ribosome entry segment (IRES) directs the synthesis of the p36 isoform of Bag-1 and that polypyrimidine tract binding protein 1 (PTB-1) and poly(rC) binding protein 1 (PCBP1) stimulate IRES-mediated translation initiation in vitro and in vivo. Here, a second...

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Détails bibliographiques
Auteurs principaux: Pickering, Becky M., Mitchell, Sally A., Spriggs, Keith A., Stoneley, Mark, Willis, Anne E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC419896/
https://ncbi.nlm.nih.gov/pubmed/15169918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5595-5605.2004
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