Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry

We have identified a novel motif which consists of the sequence (CCU)(n) as part of a polypyrimidine-rich tract and permits internal ribosome entry. A number of constructs containing variations of this motif were generated and these were found to function as artificial internal ribosome entry segmen...

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Hlavní autoři: Mitchell, Sally A., Spriggs, Keith A., Bushell, Martin, Evans, Joanne R., Stoneley, Mark, Le Quesne, John P.C., Spriggs, Ruth V., Willis, Anne E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2005
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172062/
https://ncbi.nlm.nih.gov/pubmed/15998809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339105
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