The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

MicroRNAs (miRNAs) are noncoding RNAs that base pair imperfectly to homologous regions in target mRNAs and negatively influence the synthesis of the corresponding proteins. Repression is mediated by a number of mechanisms, one of which is the direct inhibition of protein synthesis. Surprisingly, pre...

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Detalhes bibliográficos
Main Authors: Kong, Yi Wen, Cannell, Ian G., de Moor, Cornelia H., Hill, Kirsti, Garside, Paul G., Hamilton, Tiffany L., Meijer, Hedda A., Dobbyn, Helen C., Stoneley, Mark, Spriggs, Keith A., Willis, Anne E., Bushell, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449332/
https://ncbi.nlm.nih.gov/pubmed/18579786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800650105
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