The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

MicroRNAs (miRNAs) are noncoding RNAs that base pair imperfectly to homologous regions in target mRNAs and negatively influence the synthesis of the corresponding proteins. Repression is mediated by a number of mechanisms, one of which is the direct inhibition of protein synthesis. Surprisingly, pre...

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Autors principals: Kong, Yi Wen, Cannell, Ian G., de Moor, Cornelia H., Hill, Kirsti, Garside, Paul G., Hamilton, Tiffany L., Meijer, Hedda A., Dobbyn, Helen C., Stoneley, Mark, Spriggs, Keith A., Willis, Anne E., Bushell, Martin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449332/
https://ncbi.nlm.nih.gov/pubmed/18579786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800650105
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