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Mapping Peptide Hormone–Receptor Interactions Using a Disulfide-Trapping Approach

Efforts to elucidate the nature of the bimolecular interaction of parathyroid hormone (PTH) with its cognate receptor, the PTH receptor type 1 (PTHR1), have relied heavily on benzoylphenylalanine- (Bpa-) based photoaffinity cross-linking. However, given the flexibility, size, and shape of Bpa, the r...

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Detalhes bibliográficos
Main Authors: Monaghan, Paul, Thomas, Beena E., Woznica, Iwona, Wittelsberger, Angela, Mierke, Dale F., Rosenblatt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570702/
https://ncbi.nlm.nih.gov/pubmed/18459800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800122f
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