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Conformational Changes in the Parathyroid Hormone Receptor Associated with Activation by Agonist

Binding of hormones to their cognate G protein-coupled receptors (GPCRs) induces conformational shifts within the receptor based on evidence from a few hormone-receptor systems. Employing an engineered disulfide bond formation strategy and guided by a previously established model of the PTH-PTH rece...

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Autors principals: Thomas, Beena E., Woznica, Iwona, Mierke, Dale F., Wittelsberger, Angela, Rosenblatt, Michael
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366190/
https://ncbi.nlm.nih.gov/pubmed/18258686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0520
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