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PTH and PTH Antagonist Induce Different Conformational Changes in the PTHR1 Receptor
Interaction of ligands with their specific receptors is accompanied by conformational shifts culminating in receptor activation and expression of hormonal activity. Using an engineered disulfide bond formation strategy, we characterized the relative conformational changes taking place within the PTH...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Amer Soc Bone & Mineral Res.
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672208/ https://ncbi.nlm.nih.gov/pubmed/19063682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.081228 |
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