Mutation and Methylation Analysis of the Chromodomain-Helicase-DNA Binding 5 Gene in Ovarian Cancer

Chromodomain, helicase, DNA binding 5 (CHD5) is a member of a subclass of the chromatin remodeling Swi/Snf proteins and has recently been proposed as a tumor suppressor in a diverse range of human cancers. We analyzed all 41 coding exons of CHD5 for somatic mutations in 123 primary ovarian cancers a...

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Auteurs principaux: Gorringe, Kylie L, Choong, David YH, Williams, Louise H, Ramakrishna, Manasa, Sridhar, Anita, Qiu, Wen, Bearfoot, Jennifer L, Campbell, Ian G
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570601/
https://ncbi.nlm.nih.gov/pubmed/18953434
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