A novel AKT3 mutation in melanoma tumours and cell lines

Recently, a rare activating mutation of AKT1 (E17K) has been reported in breast, ovarian, and colorectal cancers. However, analogous activating mutations in AKT2 or AKT3 have not been identified in any cancer lineage. To determine the prevalence of AKT E17K mutations in melanoma, the most aggressive...

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Detaylı Bibliyografya
Asıl Yazarlar: Davies, M A, Stemke-Hale, K, Tellez, C, Calderone, T L, Deng, W, Prieto, V G, Lazar, A J F, Gershenwald, J E, Mills, G B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
Konular:
Molecular Diagnostics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570525/
https://ncbi.nlm.nih.gov/pubmed/18813315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604637
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