Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : A Novel Risk Factor for Disease-Related Early Death

OBJECTIVE—Diabetes is associated with an increased risk of death in women. Oxidative stress due to chronic hyperglycemia leads to the generation of reactive oxygen species and loss of chromosomal integrity. To clarify whether diabetes is a premature aging syndrome, we determined telomere erosion dyn...

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Autors principals: Boehm, Bernhard O., Möller, Peter, Högel, Josef, Winkelmann, Bernhard R., Renner, Wilfried, Rosinger, Silke, Seelhorst, Ursula, Wellnitz, Britta, März, Winfried, Melzner, Julia, Brüderlein, Silke
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2008
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570391/
https://ncbi.nlm.nih.gov/pubmed/18650367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0274
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