Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : A Novel Risk Factor for Disease-Related Early Death

OBJECTIVE—Diabetes is associated with an increased risk of death in women. Oxidative stress due to chronic hyperglycemia leads to the generation of reactive oxygen species and loss of chromosomal integrity. To clarify whether diabetes is a premature aging syndrome, we determined telomere erosion dyn...

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Detalhes bibliográficos
Main Authors: Boehm, Bernhard O., Möller, Peter, Högel, Josef, Winkelmann, Bernhard R., Renner, Wilfried, Rosinger, Silke, Seelhorst, Ursula, Wellnitz, Britta, März, Winfried, Melzner, Julia, Brüderlein, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570391/
https://ncbi.nlm.nih.gov/pubmed/18650367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0274
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