Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study)

BACKGROUND: Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide. A (GT)(n )dinucleotide repeat and a -413A>T single nucleotide polymorphism have been reported in the promoter region of HMOX1 to...

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Hlavní autoři: Lüblinghoff, Nicola, Winkler, Karl, Winkelmann, Bernhard R, Seelhorst, Ursula, Wellnitz, Britta, Boehm, Bernhard O, März, Winfried, Hoffmann, Michael M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678993/
https://ncbi.nlm.nih.gov/pubmed/19389234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-36
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