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‘Prion-proof’ for [PIN(+)]: Infection with in vitro-made amyloid aggregates of Rnq1p-(132–405) induces [PIN(+)]
Prions are self-propagating infectious protein conformations. The mammalian prion, PrP(Sc), responsible for neurodegenerative diseases like mad-cow and Creutzfeldt Jacob’s diseases, appears to be a β-sheet rich amyloid conformation of PrP(c) that converts PrP(c) into PrP(Sc). However, an unequivocal...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570204/ https://ncbi.nlm.nih.gov/pubmed/17097676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.069 |
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