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Analysis of the [RNQ(+)] Prion Reveals Stability of Amyloid Fibers as the Key Determinant of Yeast Prion Variant Propagation

Variation in pathology of human prion disease is believed to be caused, in part, by distinct conformations of aggregated protein resulting in different prion strains. Several prions also exist in yeast and maintain different self-propagating structures, referred to as prion variants. Investigation o...

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Detalhes bibliográficos
Main Authors: Kalastavadi, Tejas, True, Heather L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898305/
https://ncbi.nlm.nih.gov/pubmed/20442412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115303
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