Specific Mutations in the β-Catenin Gene (CTNNB1) Correlate with Local Recurrence in Sporadic Desmoid Tumors

Desmoid fibromatosis is a rare, nonmetastatic neoplasm marked by local invasiveness and relentless recurrence. Molecular determinants of desmoid recurrence remain obscure. β-Catenin deregulation has been commonly identified in sporadic desmoids although the incidence of CTNNB1 (the gene encoding β-c...

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Detalhes bibliográficos
Main Authors: Lazar, Alexander J.F., Tuvin, Daniel, Hajibashi, Shohrae, Habeeb, Sultan, Bolshakov, Svetlana, Mayordomo-Aranda, Empar, Warneke, Carla L., Lopez-Terrada, Dolores, Pollock, Raphael E., Lev, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570141/
https://ncbi.nlm.nih.gov/pubmed/18832571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080475
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