β-Catenin Mutation Status and Outcomes in Sporadic Desmoid Tumors

BACKGROUND. Mutations in the gene-encoding β-catenin, CTNNB1, are highly prevalent in sporadic desmoid tumors and may predict the risk for recurrence. We sought to determine the prevalence of CTNNB1 mutations in a large cohort of sporadic desmoid tumors and to determine whether CTNNB1 mutation statu...

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Autori principali: Mullen, John T., DeLaney, Thomas F., Rosenberg, Andrew E., Le, Long, Iafrate, A. John, Kobayashi, Wendy, Szymonifka, Jackie, Yeap, Beow Y., Chen, Yen-Lin, Harmon, David C., Choy, Edwin, Yoon, Sam S., Raskin, Kevin A., Hornicek, Francis J., Nielsen, Gunnlauger P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: AlphaMed Press 2013
Soggetti:
Sarcomas
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780636/
https://ncbi.nlm.nih.gov/pubmed/23960186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0449
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