Caspase-3 Is Enriched in Postsynaptic Densities and Increased in Alzheimer’s Disease

Progressive synaptic degeneration and neuron loss are major structural correlates of cognitive impairment in Alzheimer’s disease (AD). The mechanisms by which synaptic degeneration in AD occurs have not been established. The activation of proteins within the caspase family has been implicated in AD-...

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Detalhes bibliográficos
Main Authors: Louneva, Natalia, Cohen, Julia W., Han, Li-Ying, Talbot, Konrad, Wilson, Robert S., Bennett, David A., Trojanowski, John Q., Arnold, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570138/
https://ncbi.nlm.nih.gov/pubmed/18818379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080434
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