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Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location

BACKGROUND: An increasing number of studies report associations between variation in DTNBP1, a top candidate gene in schizophrenia, and both the clinical symptoms of the disorder and its cognitive deficits. DTNBP1 encodes dysbindin-1, reduced levels of which have been found in synaptic fields of sch...

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Hlavní autoři: Talbot, Konrad, Louneva, Natalia, Cohen, Julia W., Kazi, Hala, Blake, Derek J., Arnold, Steven E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046962/
https://ncbi.nlm.nih.gov/pubmed/21390302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016886
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