Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia

DTNBP1 (dystrobrevin binding protein 1) is a leading candidate susceptibility gene in schizophrenia and is associated with working memory capacity in normal subjects. In schizophrenia, the encoded protein dystrobrevin-binding protein 1 (dysbindin-1) is often reduced in excitatory cortical limbic syn...

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Detalhes bibliográficos
Main Authors: Carlson, Gregory C., Talbot, Konrad, Halene, Tobias B., Gandal, Michael J., Kazi, Hala A., Schlosser, Laura, Phung, Quan H., Gur, Raquel E., Arnold, Steven E., Siegel, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203764/
https://ncbi.nlm.nih.gov/pubmed/21969553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109625108
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