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Subicular Dendritic Arborization in Alzheimer’s Disease Correlates with Neurofibrillary Tangle Density

Intracellular accumulation of PHFtau in Alzheimer’s disease (AD) disrupts the neuronal cytoskeleton and other neuronal machinery and contributes to axonal and dendritic degeneration, and neuronal death. Furthermore, amyloid-β (Aβ) has been reported to be toxic to neurons and neurites. While loss of...

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Detalles Bibliográficos
Main Authors: Falke, Eric, Nissanov, Jonathan, Mitchell, Thomas W., Bennett, David A., Trojanowski, John Q., Arnold, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868320/
https://ncbi.nlm.nih.gov/pubmed/14507668
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