Subicular Dendritic Arborization in Alzheimer’s Disease Correlates with Neurofibrillary Tangle Density

Intracellular accumulation of PHFtau in Alzheimer’s disease (AD) disrupts the neuronal cytoskeleton and other neuronal machinery and contributes to axonal and dendritic degeneration, and neuronal death. Furthermore, amyloid-β (Aβ) has been reported to be toxic to neurons and neurites. While loss of...

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Bibliografische gegevens
Hoofdauteurs: Falke, Eric, Nissanov, Jonathan, Mitchell, Thomas W., Bennett, David A., Trojanowski, John Q., Arnold, Steven E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868320/
https://ncbi.nlm.nih.gov/pubmed/14507668
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