CGI-58 Is an α/β-Hydrolase within Lipid Transporting Lamellar Granules of Differentiated Keratinocytes

CGI-58 is the causative molecule underlying Dorfman-Chanarin syndrome, a neutral lipid storage disease exhibiting apparent clinical features of ichthyosis. CGI-58, associated with triacylglycerol hydrolysis, has an α/β-hydrolase fold and is also known as the α/β-hydrolase domain-containing protein 5...

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Bibliographische Detailangaben
Hauptverfasser: Akiyama, Masashi, Sakai, Kaori, Takayama, Chitoshi, Yanagi, Teruki, Yamanaka, Yasuko, McMillan, James R., Shimizu, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570125/
https://ncbi.nlm.nih.gov/pubmed/18832586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080005
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