A Palindromic Motif in the −2084 to −2078 Upstream Region is Essential for ABCA12 Promoter Function in Cultured Human Keratinocytes

ATP-binding cassette transporter family A member 12 (ABCA12) is a keratinocyte transmembrane lipid transporter that plays a critical role in preserving the skin permeability barrier. Biallelic loss of function of the ABCA12 gene is causative of some forms of recessive congenital ichthyosis, an intra...

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Hlavní autoři: Shimizu, Yoshitaka, Ogawa, Yasushi, Sugiura, Kazumitsu, Takeda, Jun-ichi, Sakai-Sawada, Kaori, Yanagi, Teruki, Kon, Atsushi, Sawamura, Daisuke, Shimizu, Hiroshi, Akiyama, Masashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206840/
https://ncbi.nlm.nih.gov/pubmed/25338618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06737
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