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The Histone Deacetylase Inhibitor Sodium Butyrate Protects Against Cisplatin-Induced Hearing Loss in Guinea Pigs

OBJECTIVE: There is a need for otoprotective agents that can be administered systemically without compromising cancer treatment. Histone deacetylase inhibitors are anticancer agents that act by upregulating the expression of cell-cycle control genes. They are also neuroprotective, leading us to hypo...

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Detalhes bibliográficos
Main Authors: Drottar, Marie, Liberman, M. Charles, Ratan, Rajiv R., Roberson, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570099/
https://ncbi.nlm.nih.gov/pubmed/16467722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.mlg.0000197630.85208.36
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