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Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss

BACKGROUND: Cisplatin chemotherapy and surgery are effective treatments for children with standardrisk hepatoblastoma but may cause considerable and irreversible hearing loss. This trial compared cisplatin with cisplatin plus delayed administration of sodium thiosulfate, aiming to reduce the inciden...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Brock, Penelope R., Maibach, Rudolf, Childs, Margaret, Rajput, Kaukab, Roebuck, Derek, Sullivan, Michael J., Laithier, Véronique, Ronghe, Milind, Dall’Igna, Patrizia, Hiyama, Eiso, Brichard, Bénédicte, Skeen, Jane, Mateos, M. Elena, Capra, Michael, Rangaswami, Arun A., Ansari, Marc, Rechnitzer, Catherine, Veal, Gareth J., Covezzoli, Anna, Brugières, Laurence, Perilongo, Giorgio, Czauderna, Piotr, Morland, Bruce, Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117111/
https://ncbi.nlm.nih.gov/pubmed/29924955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1801109
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