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Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase

GABA(B) receptors are heterodimeric G-protein coupled receptors composed of R1 and R2 subunits that mediate slow synaptic inhibition in the brain by activating inwardly-rectifying K(+) channels (GIRKs) and inhibiting Ca(2+) channels. We demonstrate here that GABA(B) receptors are intimately associat...

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Detalles Bibliográficos
Main Authors: Kuramoto, Nobuyuki, Wilkins, Megan E, Fairfax, Benjamin P, Revilla-Sanchez, Raquel, Terunuma, Miho, Warren, Noel, Tamaki, Keisuke, Iemata, Mika, Couve, Andrés, Calver, Andrew, Horvath, Zsolt, Freeman, Katie, Carling, David, Huang, Lan, Gonzales, Cathleen, Cooper, Edward, Smart, Trevor G., Pangalos, Menelas N., Moss., Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570046/
https://ncbi.nlm.nih.gov/pubmed/17224405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2006.12.015
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