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Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABA(B) receptors

Slow and persistent synaptic inhibition is mediated by metabotropic GABA(B) receptors (GABA(B)Rs). GABA(B)Rs are responsible for the modulation of neurotransmitter release from presynaptic terminals and for hyperpolarization at postsynaptic sites. Postsynaptic GABA(B)Rs are predominantly found on de...

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Detalhes bibliográficos
Main Authors: Terunuma, Miho, Vargas, Karina J., Wilkins, Megan E., Ramírez, Omar A., Jaureguiberry-Bravo, Matías, Pangalos, Menelas N., Smart, Trevor G., Moss, Stephen J., Couve, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922229/
https://ncbi.nlm.nih.gov/pubmed/20643948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000853107
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