Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABA(B) receptors

Slow and persistent synaptic inhibition is mediated by metabotropic GABA(B) receptors (GABA(B)Rs). GABA(B)Rs are responsible for the modulation of neurotransmitter release from presynaptic terminals and for hyperpolarization at postsynaptic sites. Postsynaptic GABA(B)Rs are predominantly found on de...

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Autori principali: Terunuma, Miho, Vargas, Karina J., Wilkins, Megan E., Ramírez, Omar A., Jaureguiberry-Bravo, Matías, Pangalos, Menelas N., Smart, Trevor G., Moss, Stephen J., Couve, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922229/
https://ncbi.nlm.nih.gov/pubmed/20643948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000853107
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