Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones

BACKGROUND: Mycolactones are immunosuppressive and cytotoxic polyketides, comprising five naturally occurring structural variants (named A/B, C, D, E and F), produced by different species of very closely related mycobacteria including the human pathogen, Mycobacterium ulcerans. In M. ulcerans strain...

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Hlavní autoři: Pidot, Sacha J, Hong, Hui, Seemann, Torsten, Porter, Jessica L, Yip, Marcus J, Men, Artem, Johnson, Matthew, Wilson, Peter, Davies, John K, Leadlay, Peter F, Stinear, Timothy P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569948/
https://ncbi.nlm.nih.gov/pubmed/18840298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-462
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