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Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

Mycolactones are a family of highly related macrocyclic polyketides that exhibit immunosuppressive and cytotoxic properties. First discovered in 1999, they are the primary virulence factors produced by the environmental human pathogen Mycobacterium ulcerans, the causative agent of Buruli ulcer, and...

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Detalhes bibliográficos
Main Authors: Hong, Hui, Demangel, Caroline, Pidot, Sacha J., Leadlay, Peter F., Stinear, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730631/
https://ncbi.nlm.nih.gov/pubmed/18497894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b803101k
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