Lymphoproliferative activity of Pseudomonas exotoxin A is dependent on intracellular processing and is associated with the carboxyl-terminal portion.

Pseudomonas aeruginosa exotoxin A (PE) represents a microbial superantigen that requires processing by accessory cells in order to induce the proliferation of V beta 8-bearing murine T lymphocytes. In this study, we have observed that PE requires intracellular processing by a protease in order to in...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Legaard, P K, LeGrand, R D, Misfeldt, M L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.4.1273-1278.1992
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