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Processing of Pseudomonas aeruginosa Exotoxin A Is Dispensable for Cell Intoxication
Exotoxin A is a major virulence factor of Pseudomonas aeruginosa. This toxin binds to a specific receptor on animal cells, allowing endocytosis of the toxin. Once in endosomes, the exotoxin can be processed by furin to generate a C-terminal toxin fragment that lacks the receptor binding domain and i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708563/ https://ncbi.nlm.nih.gov/pubmed/19380469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01390-08 |
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